Product Description Model NO.: CAS159752-10-0 Alias: Ibutamoren Mk-677 Molecular Weight: 528.664 Appearance: Appearance Specification: GMP, ISO HS Code: 3001200010 Name: Ibutamoren Molecular Formula: C27h36n4o5s Purity: 99% Trademark: gongchuang Origin: Hubei 1.Basic Details

Product Name	Ibutamoren MK-677
CAS NO.	159634-47-6
Alias	MK-0677
Molecular formula	C27H36N4O5S
Molecular weight	528.664
Purity	99%
Grade	Pharmaceutical Grade
Appearance	White Powder

2.Description

Ibutamoren (developmental code names MK-677, MK-0677, L-163,191) is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a G-H secretagogue,mimicking the G-H-stimulating action of the endogenous hormone ghrelin.It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including G-H and insulin-like IGF-1, but without affecting cortisol levels.It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with G-H deficiency,and human studies have shown it to increase both muscle mass and bone mineral density,making it a promising therapy for the treatment of frailty in the elderly.It also alters metabolism of body fat and so may have application in the treatment of obesity.

3.Effect

Inhibits the signaling of somatostatin receptors
Slows down the activity of somastostatin in the system
Improves somatotroph signaling in GHRH
Amplifies and increases the overall production and release of GHRH


Benefits
In a study on it's effects on catabolic states, a once daily oral dose of 25mgs was given to healthy young men subjected to short-term diet-induced nitrogen wasting. After 7 days of this dose, the subjects showed a sustained increase in serum concentration of IGF-1 and Growth Hormone; in addition, the nitrogen wasting was reversed, showing great potential for treatment of conditions involving muscle wasting.
Trials testing the effects of this GHS on fighting obesity showed an increase in lean body mass, but neither total, nor visceral adipose tissue was effected. This study gave subjects 25mgs of Nutrobal per day for 8 weeks. The subjects showed an increase in basal metabolic rate after 2 weeks, and an increase in serum levels of GH, IGF-1 and IGF-1 binding protein-3. Increase in lean body mass was hypothesized to be caused by an increase in calorie deposition into the muscle and appetite decrease as opposed to reducing fat storage directly.
A study done for the treatment of osteoporosis and bone mineral density showed some increase in bone density, so there is a true impact on bone mineral density. This can help with injury recovery during your cycle.
Other possible benefits of Nutrobal are associated with improved sleep, improved complexion, increase in energy levels, increase nitrogen retention, increase strength and an improved sense of well being. In addition, some studies also suggest that an increased immune system response was caused by Nutrobal (Mk-677), meaning it boosts the immune system to a degree.

4.COA

TEST	ACCEPTANCE CRITERLA	RESULTS
	TLC	Positive
Identification	UV spectrum	Positive
	IR spectrum	Positive
Characteristics	White to yellowish-white crystalline powder	conform
Melting point	32 ~ 37ºC	33~36ºC
Specific optical rotation	+77°~+82°	+79.3°
Loss on drying	≤0.5%	0.15%
Assay	97 ~ 103%	99.08%
Free heptanoic acid	≤0.2 %	0.10%
Related substances	≤2%	Pass
	Acetone ≤100ppm	Pass
Residual solvents(GC)	Methanol ≤100ppm	Pass
	Pyridine ≤100ppm	Pass
Particle size		Pass

How to proceed your order: Step 1: Please let me know the items you are favorable, quantities, and the destination country  Step 2: You confirm all detail, and offer purchasing order. Step 3: We send the detail price of our product and offer the suitable shipping method for reference. Step 4: You confirm the order and pay mony 100% in advance and send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements. Step 5: We arrange the shipment according to your requirements, and tracking code will be offered after claiming the payment within 24h, then you can track your parcel at any moment. Step 6: We offer after-sales services after service after you receive your parcel.  

Our Competitive Advantage:   Professional Manufacture: Hubei Yuancheng Saichuang Technology Co., Ltd. is a legit and professional pharmaceutical manufacturer specialized in steroid hormone powders, steroid injectable liquids, peptides,pharmaceutical raw materials & its intermediate.Our factory is in Nanhu Shouyi Industrial District, just by the side of the beautiful South Lake in Wuhan. Our company integrates R&D, producing, operating and marketing into an organic whole. All products are produced under GMP conditions according to Standard Operation Procedure(SOP),not from little underground labs or black markets, so the quality is guaranteed. We have authority of export and import, and have experience of export for more than 10 years.   Minimum Order: 10-100 grams.our min packing of each powder is 10g or 100g, but some expensive powder can be bought at several grams.   Payment Method: Western Union,Money Gram,T/T.   Professional Delivery: By courier ( EMS, DHL, Fedex, UPS,TNT) is prefered, bulk order can be negotiated.5-7 business days delivery in timely manner. Tracking No. is available ,we can provide you latest tracking of our customers to check validity of delivery if you need.   Discreetly Packing: Safe and professional disguised package can be guaranteed.   Plenty In Stock: Most of powders are in stock.We export over 1000 kilograms of Steroid Powder per month.   High Delivery Rate: Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%,  As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.    
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