Product Description Model NO.: 81409-90-7 Customized: Customized Suitable for: Adult Purity: >98% CAS: 81409-90-7 MW: 451.6 Appearance: White Powder Specification: enterprise standard HS Code: 2939630090 Powder: Yes Certification: ISO 9001 State: Solid Name: Cabergoline Mf: C26h37n5o2 Assay: 98% Trademark: Saichuang Origin: Wuhan Cabergoline
CAS: 81409-90-7
MF: C26H37N5O2
MW: 451.6
Purity:98%
Appearance:white powder
Cabergoline an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. Rat studies show cabergoline has a direct inhibitory effect on pituitary lactotroph (prolactin) cells.It is frequently used as a first-line agent in the management ofprolactinomas due to higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine.
Uses:
hyperprolactinemia
adjunctive therapy of prolactin-producing pituitary gland tumors (prolactinomas);
monotherapy of Parkinson's disease in the early phase;
combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinson's disease;
in some countries also: ablactation and dysfunctions associated with hyperprolactinemia (amenorrhea, oligomenorrhea, anovulation, nonpuerperal mastitis and galactorrhea);
treatment of uterine fibroids.
adjunctive therapy of acromegaly, cabergoline has low efficacy in suppressing growth hormone levels and is highly efficient in suppressing hyperprolactinemia that is present in 20-30% of acromegaly cases; growth hormone and prolactin are similar structurally and have similar effects in many target tissues, therefore targeting prolactin may help symptoms when growth hormone secretion can not be sufficiently controlled by other methods

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