Product Description
Model NO.: CAS 136-47-0 CAS: 136-47-0 Melting Point: 147 ~ 150 Oc Product Package: as You Request Grade: Pharm Trademark: Yuancheng Saichuang Origin: China Name: Tetracaine Hydrochloride Einecs: 205-248-5 Character: White Crystalline Powder Product Standard: UPS Skype: Trustful_3 Specification: SGS HS Code: 2801301000 Anaesthesia Powder Tetracaine Hydrochloride / HCl 136-47-0
1.Quick Details
Product Name | tetracaine hydrochloride | Other name | Tetracaine HCl; 2-dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride; Anethaine; Butethanol; Curtacain; Decicain; Pantocaine;Tonexol; Tetracaine HCL |
CAS | 136-47-0 | EINECS | 205-248-5 |
Purity | 99% | melting point | 147 ~ 150 ºC |
character | white crystalline powder | Function | A local anesthetic used topically in opthalmology. |
2.Security term
1.S26In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
2.S36/37Wear suitable protective clothing and gloves.
3.S45In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Dangerous term
1.R25Toxic if swallowed.
2.R36Irritating to eyes.
3.R43 May cause sensitization by skin contact.
3.Application
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent
local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and
it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine
receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker
of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium
release events, while at high concentrations, tetracaine blocks release completely.
Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5 (per myriad), a half per mille (0.5‰), or
.05 per cent (1 part in 2000) adrenaline, and 4 or 10 per centhydrochloride used in ear, nose & throat
surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially
when children have been injured in the eye, ear, or other sensitive locations.
It is on the World Health Organization's List of Essential Medicines, a list of the most important
medication needed in a basic health system.
A systematic review and meta-
analysis of randomised controlled trials investigated tetracaine for use in emergency departments,
especially for IV cannulation in children, in view of its analgesic and cost-
saving properties - however it did not find a statistically significant improvement in first attempt
cannulations.
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